In primary neurulation, 

cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate into the body, and separate from the surface ectoderm to form an underlying hollow tube.

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#Id: 976

#Unit 5. Developmental Biology

Siamois and Twin inducing the activation of the neuroepithelium genes –Foxd4 and Sox11

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#Id: 977

#Unit 5. Developmental Biology

In Drosophila, BMP homologue Decapentaplegic (Dpp)

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#Id: 978

#Unit 5. Developmental Biology

In Drosophila,SOG protein is a homologue of Chordin.

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#Id: 979

#Unit 5. Developmental Biology

Wnt inhibitors secreted by the organizer are Dickkopf, Cerberus, Frzb & IGF

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#Id: 980

#Unit 5. Developmental Biology

Two organizer proteins, inhibit Wnt proteins during gastrulation Tiki and Notum

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#Id: 981

#Unit 5. Developmental Biology

Brain formation requires,  inhibiting both the Wnt and  BMP pathways.