Negative costimulation

TLS Online TPP Program

#Id: 9374

#Unit 4. Cell Communication and Cell Signaling

Like SOCS proteins in the cytokine signaling, 

Smad7 also recruits an E3 ubiquitin ligase that targets TGF-β receptors for degradation.

TLS Online TPP Program

#Id: 10176

#Unit 6. System Physiology – Plant

Conversely bioactive gibberellin and the GID1 receptor enhance DELLA repressor degradation, while GA2ox blocks DELLA repressor degradation

TLS Online TPP Program

#Id: 10526

#Unit 4. Cell Communication and Cell Signaling

After cleavage by caspase-3, truncated XKR8, together with either basigin (BSG) or neuroplastin (NPTN), undergoes dimerization and activation and translocates

phospholipids in both directions.

TLS Online TPP Program

#Id: 6542

#Unit 7. System Physiology – Animal

Fat and muscle cells express large amounts of the insulin-responsive glucose transporter GLUT4

TLS Online TPP Program

#Id: 9949

#Unit 4. Cell Communication and Cell Signaling

Resistance to leishmaniasis correlates well with the production of IFN-ϒ and the development of a TH1 response.

Strains of mice that are naturally resistant to Leishmania develop a TH1 response and produce IFN-ϒ upon infection.