Genetic redundancy means that two or more genes are performing the same function and that inactivation of one of these genes has little or no effect on the biological phenotype

Redundancy seems to be widespread in genomes of higher organisms

TLS Online TPP Program

#Id: 1545

#Unit 2. Cellular Organization

Katanin promotes breakage by extracting tubulin subunits from the wall of the microtubule (also releases microtubules from MTOCs). 

 

TLS Online TPP Program

#Id: 1546

#Unit 2. Cellular Organization

Plectin links microtubules to intermediate filaments.

 

TLS Online TPP Program

#Id: 1547

#Unit 2. Cellular Organization

Taxol, 

A plant alkaloid from the Pacific yew tree

Binds microtubules and stabilizes them against depolymerization

TLS Online TPP Program

#Id: 1548

#Unit 2. Cellular Organization

Nocodazole and colchicine

TLS Online TPP Program

#Id: 1549

#Unit 2. Cellular Organization

Two main families of motor proteins mediate transport along microtubules:

Kinesins 

Dyneins

TLS Online TPP Program

#Id: 1550

#Unit 2. Cellular Organization

Kinesin-1 powers anterograde transport of vesicles down axons toward the (+) ends of microtubules.