Benzo(a)pyrene

(found in cigarette smoke & coal tar) undergoes metabolic activation by cytochrome P-450 in the lungs to form a potent mutagen

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#Unit 7. System Physiology – Animal

Auditory hair cells in the Organ of Corti are the sites of auditory transduction

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#Unit 7. System Physiology – Animal

The nerves that serve the organ of Corti are contained in the vestibulocochlear nerve (CN VIII)

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#Unit 7. System Physiology – Animal

The hair cells are arranged in four rows: 

Three rows of outer hair cells (20,000)

One row of inner hair cells (3500)

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#Unit 7. System Physiology – Animal

Covering the rows of hair cells is a thin, viscous, but elastic tectorial membrane in which the tips of the outer hair cells are embedded

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#Unit 7. System Physiology – Animal

The processes of the hair cells are bathed in endolymph, whereas their bases are bathed in perilymph, this arrangement is necessary for the normal production of

receptor potentials

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#Unit 7. System Physiology – Animal

Except in the cochlea, the kinocilium, is a true but nonmotile cilium with nine pairs of microtubules around its circumference and a central pair of microtubules. one of the largest processes and has a clubbed end. 

(The kinocilium is lost from the hair cells of the cochlea in adult mammals)