Chronic myelogenous leukemia, 

a common leukemia in humans, associated with the Philadelphia chromosome

TLS Online TPP Program

#Id: 10056

#Unit 4. Cell Communication and Cell Signaling

Cell-adhesion molecules (CAMs) mediate direct cell-cell adhesions.

TLS Online TPP Program

#Id: 10057

#Unit 4. Cell Communication and Cell Signaling

Adhesion receptors mediate cell-matrix adhesions

TLS Online TPP Program

#Id: 10058

#Unit 4. Cell Communication and Cell Signaling

Homophilic Binding 

A CAM on one cell can directly bind to the same kind of CAM on an adjacent cell

TLS Online TPP Program

#Id: 10059

#Unit 4. Cell Communication and Cell Signaling

Heterophilic Binding

A CAM on one cell can directly bind to a different class of CAM on an adjacent cell

TLS Online TPP Program

#Id: 10060

#Unit 4. Cell Communication and Cell Signaling

The formation of many cell-cell adhesions entails two types of molecular interactions:

1.Trans binding interactions 

2. Cis binding interactions

TLS Online TPP Program

#Id: 10061

#Unit 4. Cell Communication and Cell Signaling

Trans interactions (intercellular or adhesive interactions)

CAMs on one cell bind to CAMs on an adjacent cell.