Three mechanisms for LOH of tumor-suppressor genes:

Inactivating mutation or deletion

Chromosome missegregation

Mitotic recombination

TLS Online TPP Program

#Id: 3095

#Unit 3. Fundamental Processes

Once replication has started, it continues until the entire genome has been duplicated.

TLS Online TPP Program

#Id: 3097

#Unit 3. Fundamental Processes

The unit of DNA in which an individual act of replication occurs is called the replicon

TLS Online TPP Program

#Id: 3100

#Unit 3. Fundamental Processes

It has an origin at which replication is initiated. It may also have a terminus at which replication stops.

TLS Online TPP Program

#Id: 3102

#Unit 3. Fundamental Processes

An origin at which replication is initiated. It may also have a terminus at which replication stops.

TLS Online TPP Program

#Id: 3103

#Unit 3. Fundamental Processes

Replicon" is usually applied to eukaryotic chromosomes to describe a unit of replication that contains an origin.

TLS Online TPP Program

#Id: 3104

#Unit 3. Fundamental Processes

A plasmid is an autonomous circular DNA that constitutes a separate replicon.