A mutation, valine to glutamine in the TM region of the HER2 receptor causes dimerization of the receptor, even in the absence of the ligand, transforming it into the oncoprotein NEU, a constitutively active protein tyrosine kinase.

TLS Online TPP Program

#Id: 1257

#Unit 7. System Physiology – Animal

ADH (Vasopressin) contraction of vascular smooth muscle

TLS Online TPP Program

#Id: 1258

#Unit 7. System Physiology – Animal

The receptor for ADH on vascular smooth muscle V1 receptor, which is coupled via a Galpha q protein.

TLS Online TPP Program

#Id: 1259

#Unit 7. System Physiology – Animal

Central diabetes insipidus – No ADH Nephrogenic diabetes insipidus - principal cells are unresponsive to ADH

TLS Online TPP Program

#Id: 1260

#Unit 7. System Physiology – Animal

The cells of the adrenal cortex contain large amounts of smooth endoplasmic reticulum, which is involved in the steroid-forming process.

TLS Online TPP Program

#Id: 1261

#Unit 7. System Physiology – Animal

The hormones of the adrenal cortex are derivatives of cholesterol.

TLS Online TPP Program

#Id: 1262

#Unit 7. System Physiology – Animal

The adrenal cortex secretes three classes of steroid hormones:

Glucocorticoids

Mineralocorticoids

Androgens