7,8-diol-9,10-epoxide is responsible for cancer development forms an adduct with guanine:

(+)-trans-anti-B-(a)-P-N superscript 2-d G adduct

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#Unit 5. Developmental Biology

In the presence of Nodal, the Pitx2 gene is activated

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#Unit 5. Developmental Biology

On the right side of the embryo, activin is expressed, along with activin receptor IIa. This activates Fgf8, a protein that blocks expression of the gene for Cerberus.

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#Unit 5. Developmental Biology

In the absence of Cerberus, Nodal is not activated and thus Pitx2 is not expressed

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#Unit 5. Developmental Biology

Drosophila eggs undergo Superficial cleavage.

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#Unit 5. Developmental Biology

In the Drosophila egg, karyokinesis occurs without cytokinesis to create a syncytium.

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#Unit 5. Developmental Biology

In Drosophila, during the ninth division cycle- Pole cells determination