#Id: 7549
#Unit 6. System Physiology – Plant
In the nucleus, gibberellin binds to the GID1 receptor and induces a conformational change in the N-terminal domain of the receptor, allowing the receptor to interact with the TVHYNP and DELLA domains of the DELLA repressor.
The formation of the GID1-repressor complex promotes the interaction between the repressor and the E3 ubiquitin ligase SCF-SLY, leading to the ubiquitination and degradation of the DELLA repressor by the 26S proteasome.