During S phase and mitosis, 

Cdh1 is phosphorylated, Cdh1 dissociates from APC/C, and APC/C becomes inactive.

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#Unit 1. Molecules and their Interaction Relevant to Biology

The van der Waals interaction primarily depends on interatomic distance.

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#Unit 1. Molecules and their Interaction Relevant to Biology

Fundamental Behind VWI is DIPOLE

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#Unit 1. Molecules and their Interaction Relevant to Biology

Electrons are constantly are moving in an atom, so dipoles are probable of occurring.

A dipole is defined as molecules or atoms with equal and opposite electrical charges separated by a small distance.

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#Unit 1. Molecules and their Interaction Relevant to Biology

There are four major DIPOLES that decide VWI

1. spontaneous (or instantaneous) dipoles

2. Dipole-Dipole Interaction

3. Induced Dipoles

4. Spontaneous Dipole-Induced Dipole Interaction

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#Unit 1. Molecules and their Interaction Relevant to Biology

Spontaneous (or instantaneous) dipoles

When groups of electrons move to one end of the atom, it creates a dipole. 

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#Unit 1. Molecules and their Interaction Relevant to Biology

Dipole-Dipole Interaction

Dipole-Dipole interactions occur between molecules that have permanent dipoles; these molecules are also referred to as polar molecules.