Active Immunization

TLS Online TPP Program

#Id: 5783

#Unit 7. System Physiology – Animal

The primary hormone secreted by the thyroid is thyroxine (T4) along with much lesser amounts of triiodothyronine (T3)

TLS Online TPP Program

#Id: 5784

#Unit 7. System Physiology – Animal

Basolateral membranes of thyrocytes contain a symporter Na+/I –symporter (NIS) 

TLS Online TPP Program

#Id: 5785

#Unit 7. System Physiology – Animal

Process of concentrating the iodide in the cell is called iodide trapping

TLS Online TPP Program

#Id: 5786

#Unit 7. System Physiology – Animal

Na+/I – symporter (NIS) is capable of producing intracellular I – concentrations that are 20– 40 times as great as the concentration in plasma

TLS Online TPP Program

#Id: 5787

#Unit 7. System Physiology – Animal

Wolff –Chaikoff effect large doses of iodide act directly on the thyroid to produce a mild and transient inhibition of organic binding of iodide and hence of hormone synthesis.

TLS Online TPP Program

#Id: 5788

#Unit 7. System Physiology – Animal

Thyroid stimulating hormone induces both NIS expression and the retention of NIS in the basolateral membrane.