Potency, commitment, specification, induction, competence, determination and differentiation; morphogenetic gradients; cell fate and cell lineages; stem cells; genomic equivalence and the cytoplasmic determinants; imprinting; mutants and transgenics in analysis of development

TLS Online TPP Program

#Id: 2110

#Unit 8. Inheritance Biology

Deletions are lethal in the homozygous state because all copies of any essential genes located in the deleted region are missing.

TLS Online TPP Program

#Id: 2111

#Unit 8. Inheritance Biology

Heterozygous condition may produce imbalances in the amounts of gene products similar to those produced by extra gene copies.

TLS Online TPP Program

#Id: 2112

#Unit 8. Inheritance Biology

Pseudodominance- Recessive allele owing to a deletion on the homologous chromosome.

TLS Online TPP Program

#Id: 2113

#Unit 8. Inheritance Biology

Haploinsufficiency- One copy of the gene is missing, a mutant phenotype is produced.

TLS Online TPP Program

#Id: 2114

#Unit 8. Inheritance Biology

Deletions can be detected cytologically by studying the banding patterns in stained chromosomes.

TLS Online TPP Program

#Id: 2115

#Unit 8. Inheritance Biology

Large aberrations can be detected by examination of mitotic chromosomes that have been stained with banding agents such as quinacrine or Giemsa.