Histone biogenesis is primarily controlled by the regulation of histone mRNA abundance during the cell cycle. At this G1/S transition, the abundance of histone mRNAs is increased more than 30-fold due to elevated transcription; this process is regulated by the Cyclin E/Cdk2 complex.

TLS Online TPP Program

#Id: 2614

#Unit 13. Methods in Biology

To more accurately validate the predicted target genes of miRNAs and exactly determine the cleavage sites within the targets, an integrated strategy comprising RLM-RACE, Poly(A) Polymerase-Mediated (PPM)-RACE, and qRT-PCR was developed.

TLS Online TPP Program

#Id: 1101

#Unit 2. Cellular Organization

P3 ATPases transports-H+ & Mg+2 

7. P4 ATPases are flippases, transports phospholipids 

PS, PC and PE.

TLS Online TPP Program

#Id: 8415

#Unit 2. Cellular Organization

Dilated cardiomyopathy

Minor missense mutations in the cardiac actin gene

TLS Online TPP Program

#Id: 6990

#Unit 5. Developmental Biology

Pluripotency A stem cell that has the potential to differentiate into any of three germ layers(endoderm , mesoderm & ectoderm). Eg-all embryonic cells

TLS Online TPP Program

#Id: 7957

#Unit 2. Cellular Organization

Immediately after the entire precursor, Glc3Man9(GlcNAc)2 is transferred to a nascent polypeptide, three different enzymes, called  glycosidases, remove all three glucose residues and one particular mannose residue.