Nurturing Life Sciences
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The Birth of a Gene - Duplication is the most common way that new genes arise in eukaryotes.
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#Unit 2. Cellular Organization
Nucleosomes that contain linker H1 histones are referred to as chromatosomes.
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Lysine in the histone tails are the most common targets of modification.
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Acetylation, methylation, ubiquitylation, and sumoylation all occur on the free epsilon amino group of lysine.
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Acetylation neutralizes the positive charge of lysine so disrupts DNA Histone interactions.
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lysine methylation retains the positive charge, and lysine can be mono-, di-, or trimethylated.
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Histone codes are specific and conserved residues that undergoes to modification and changes expression of chromatin.