TRCF binds to double-stranded DNA upstream of the polymerase and uses the ATPase motor to translocate along the DNA until it encounters the stalled RNA polymerase.

TLS Online TPP Program

#Id: 9590

#Unit 11. Evolution and Behavior

TLS Online TPP Program

#Id: 6046

#Unit 10. Ecological Principles

TLS Online TPP Program

#Id: 5050

#Unit 3. Fundamental Processes

DnaA is an ATP-binding protein.

The first stage in initiation is binding of the DnaA-ATP protein complex to the fully methylated oriC sequence.

This takes place in association with the inner membrane. DnaA is in the active form only when bound to ATP.

DnaA has intrinsic ATPase activity that hydrolyzes ATP to ADP and thus inactivates itself when the initiation stage ends.

TLS Online TPP Program

#Id: 5858

#Unit 10. Ecological Principles

The number of species should increase with increasing island size. This is also known as the species-area hypothesis.

TLS Online TPP Program

#Id: 6874

#Unit 3. Fundamental Processes

Heterochromatin and RNAi are required to establish the human CenH3 homolog, CENP-A, at centromeres.