The coupling between transcription and translation has important consequences for rho action. Rho must first have access to RNA upstream of the transcription complex and then moves along the RNA to catch up with RNA polymerase. 

TLS Online TPP Program

#Id: 393

#Unit 2. Cellular Organization

Using the clock analogy again, the DNA associated with H2A.H2B is located from 5 o’clock to 9 o’clock on either face of the nucleosome disc.

TLS Online TPP Program

#Id: 1396

#Unit 4. Cell Communication and Cell Signaling

All small GTPases of the Ras superfamily, Cdc42, Rac, and Rho act as molecular switches, inactive in the GDP-bound state and active in the GTP-bound state.

TLS Online TPP Program

#Id: 3622

#Unit 3. Fundamental Processes

Mutations that remove the 2'-OH of the A residue at the 3' end of the P-site tRNA result in a 10⁶ -fold reduction in catalysis rates.

TLS Online TPP Program

#Id: 5552

#Unit 7. System Physiology – Animal

The principal cells are the primary sites of action of the potassium-sparing diuretics, including spironolactone, eplerenone, amiloride, and triamterene

TLS Online TPP Program

#Id: 3649

#Unit 3. Fundamental Processes

Valine cannot coordinate the Zn2+ in this way and hence does not undergo adenylation by ThrRS. A separate editing site deal with misacylated Ser–tRNAThr.