Allolactose binds to a part of the Lac repressor distinct from its DNA-binding domain.

TLS Online TPP Program

#Id: 10381

#Unit 4. Cell Communication and Cell Signaling

IL-4 increases expression of class II molecules in resting B cells, turning them into more efficient APCs.

TLS Online TPP Program

#Id: 10382

#Unit 4. Cell Communication and Cell Signaling

Expression of class II molecules by B cells is down-regulated by IFN-¥.

TLS Online TPP Program

#Id: 10383

#Unit 4. Cell Communication and Cell Signaling

Corticosteroids and prostaglandins can also decrease expression of class II MHC molecules.

TLS Online TPP Program

#Id: 10384

#Unit 4. Cell Communication and Cell Signaling

Class II MHC transcriptional activator called CIITA and another transcription factor called RFX, have both been shown to activate the promoter of class II MHC genes.

Defects in these transcription factors cause one form of bare lymphocyte syndrome.

TLS Online TPP Program

#Id: 10385

#Unit 4. Cell Communication and Cell Signaling

Cross-presentation

TLS Online TPP Program

#Id: 10386

#Unit 4. Cell Communication and Cell Signaling

Presentation of nonpeptide antigens derived from pathogens involves the nonclassical class I–like CD1 molecule