The most useful range for proteins is above 230 nm, where there are absorptions from aromatic side chains.

TLS Online TPP Program

#Id: 1471

#Unit 4. Cell Communication and Cell Signaling

The extracellular matrix is a dynamic, complex meshwork of proteins and polysaccharides that contributes to the structure and function of a tissue. 

TLS Online TPP Program

#Id: 1472

#Unit 4. Cell Communication and Cell Signaling

The major classes of ECM molecules are: 

• Proteoglycans

• Collagens

• Multi-adhesive matrix proteins

 

TLS Online TPP Program

#Id: 1473

#Unit 4. Cell Communication and Cell Signaling

Integrins function as adhesion receptors and CAMs in wide variety of epithelial and nonepithelial cells, mediating cell-matrix and cell-cell interactions.

TLS Online TPP Program

#Id: 1474

#Unit 4. Cell Communication and Cell Signaling

All integrins bind to proteins that consist of tripeptide sequence Arg-Gly-Asp, called the RGD motif

TLS Online TPP Program

#Id: 1555

#Unit 4. Cell Communication and Cell Signaling

Wnts are paracrine factors that make up a large family of cysteine-rich glycoproteins.

TLS Online TPP Program

#Id: 1556

#Unit 4. Cell Communication and Cell Signaling

The defining property of Wnt proteins is 22 cysteine residues, which form disulfide bridges that maintain a globular secondary structure.