The major role of ORC is to identify the origin to the Cdc6 and MCM proteins that control initiation and licensing.

TLS Online TPP Program

#Id: 6872

#Unit 3. Fundamental Processes

RNA-induced silencing complex (RISC/RITS) remodeling complexes to chromatin to form heterochromatin in telomeres.

The siRNA complex promotes methylation of histone H3K9 by the Clr4 methyltransferase (also known as KMT1, a homolog of Drosophila Su[Var]3–9). H3K9 methylation recruits the S. pombe homolog of HP1, Swi6.

TLS Online TPP Program

#Id: 1546

#Unit 2. Cellular Organization

Plectin links microtubules to intermediate filaments.

 

TLS Online TPP Program

#Id: 10520

#Unit 4. Cell Communication and Cell Signaling

In normal vertebrate cells, ATP-powered phospholipid flippases  (members of the ABC transporter) called 

ATP11A and ATP11C

TLS Online TPP Program

#Id: 6005

#Unit 3. Fundamental Processes

Orc2-5 binds strongly; Orc6 binds weakly to ARS and has a nuclear localization signal that must be activated by the cyclin/ CDK kinase during the G1 to S transition.

TLS Online TPP Program

#Id: 9356

#Unit 4. Cell Communication and Cell Signaling

RI will not bind to RII unless RII is bound to TGF-β.