FEN 1 functions as an endonuclease, but it also has a 5 '-3' exonuclease activity. In DNA repair reactions, FEN 1 may cleave next to a displaced nucleotide and then use its exonuclease activity to remove adjacent material.

TLS Online TPP Program

#Id: 5309

#Unit 7. System Physiology – Animal

Closure of the AV valves produces the first heart sound (S1).

TLS Online TPP Program

#Id: 5310

#Unit 7. System Physiology – Animal

During isovolumetric Ventricular contraction, the volume of the ventricle does not change because all valves are closed.

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#Id: 5311

#Unit 7. System Physiology – Animal

Period of isovolumetric ventricular contraction lasts, until the pressures in the left and right ventricles,exceed the pressures in the aorta & pulmonary artery.

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#Id: 5312

#Unit 7. System Physiology – Animal

During Isovolumetric Ventricular Contraction QRS waves appear as a result of electrical depolarization of the ventricles

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#Id: 5313

#Unit 7. System Physiology – Animal

Rapid Ventricular Ejection When ventricular pressure becomes greater than aortic pressure, the aortic valve opens (left heart).

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#Id: 5314

#Unit 7. System Physiology – Animal

Rapid Ventricular Ejection

Blood is rapidly ejected from the left ventricle into the aorta through aortic valve, driven by the pressure gradient between the left ventricle and the aorta.