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TLS Online TPP Program

#Id: 3355

If 10 protons are pumped out per NADH and 4 must flow in to produce 1 ATP, the proton-based P/O ratio is 2.5 for NADH as the electron donor and 1.5 (6/4) for succinate.



#Unit 6. System Physiology – Plant #ATP Synthesis #Part B Pointers
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TLS Online TPP Program

#Id: 8325

#Unit 2. Cellular Organization

Critical concentration (Cc)
minimal concentration of monomers at which filaments form
TLS Online TPP Program

#Id: 8326

#Unit 2. Cellular Organization

The two ends of microfilament polymerize at different rates:
fast-growing end - plus end
slow-growing end - minus end
TLS Online TPP Program

#Id: 8327

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8328

#Unit 2. Cellular Organization

Hydrolysis of the bound nucleotide reduces the binding affinity of the subunit for neighbouring subunits and makes it more likely to dissociate from each end of the filament.
T form that adds to the filament and the D form that leaves.
TLS Online TPP Program

#Id: 8329

#Unit 2. Cellular Organization

Treadmilling
Because the critical concentrations for the two ends are different, at steady state the free ATP–G-actin will be intermediate between Cc+ and Cc - , so the (+)end will grow and the (-)end will lose subunits.
TLS Online TPP Program

#Id: 8330

#Unit 2. Cellular Organization