The cytosolic isozymes has two distinct function, It catalyzes the conversion of citrate to isocitrate, providing the substrate for a cytosolic isocitrate dehydrogenase that generates NADPH as reducing power for fatty acid synthesis and other anabolic processes in the cytosol. It also has a role in cellular iron homeostasis

TLS Online TPP Program

#Id: 1184

#Unit 7. System Physiology – Animal

When light strikes the outer segment of Rod cells: 

Na + channels closed 

Hyperpolarizing receptor potential

TLS Online TPP Program

#Id: 1185

#Unit 7. System Physiology – Animal

The hyperpolarization of rod cells:

  Reduces the release of glutamate

  Generates a signal in the bipolar cells

  Leads to AP in ganglion cells 

TLS Online TPP Program

#Id: 1186

#Unit 7. System Physiology – Animal

Retinal ganglion cells contain melanopsin.

TLS Online TPP Program

#Id: 1187

#Unit 7. System Physiology – Animal

Types of retinal ganglion cells:

  large ganglion cells (magno, or M cells)

  small ganglion cells (parvo, or P cells)

TLS Online TPP Program

#Id: 1188

#Unit 7. System Physiology – Animal

A lesion that interrupts one optic nerve causes blindness in that eye.

TLS Online TPP Program

#Id: 1189

#Unit 7. System Physiology – Animal

Homonymous (same side of both visual fields) Hemianopia (half blindness)