The H3.H4 tetramer forms the top half of the histone octamer. Histone H3.H4 tetramers occupy a key position in the nucleosome by binding the middle and both ends of the DNA

TLS Online TPP Program

#Id: 6807

#Unit 3. Fundamental Processes

The precursor RNA for the siRNA pathway is a longer dsRNA. As a consequence of this different initial substrate, Drosha is not needed for the generation of siRNAs. Cleavage by Dicer is still required, however, and again generates a suitable 21- to 22-nucleotide RNA for incorporation into RISC.

TLS Online TPP Program

#Id: 9157

#Unit 11. Evolution and Behavior

Loop method for inbreeding coefficient

Summation of all possible loop (1/2)ⁿ

TLS Online TPP Program

#Id: 8860

#Unit 2. Cellular Organization

During S phase

DNA-bound G1 cohesins Convert into cohesive complexes by cohesin acetyl transferases (CoATs)

which acetylate Smc3 subunit & prevents unloading of cohesins by Pds5-Wapl, thereby stabilizing the cohesins on chromosomes.

TLS Online TPP Program

#Id: 3026

#Unit 3. Fundamental Processes

Priming activity is required to provide 3'-0H ends to start off the DNA chains on both the leading and lagging strands.

TLS Online TPP Program

#Id: 7786

#Unit 2. Cellular Organization

NLSs were first discovered through the analysis of mutations of the gene for large T-antigen encoded by simian virus 40 (SV40).