About 75% of the charged residues in proteins are members of ion pairs that are located mostly on the protein surface.

Despite the strong electrostatic attraction interactions contribute little to the stability of a native protein.

TLS Online TPP Program

#Id: 3612

#Unit 3. Fundamental Processes

The initiation codon AUG is the most common signal for the beginning of a
polypeptide in all cells.

TLS Online TPP Program

#Id: 3613

#Unit 3. Fundamental Processes

The termination codons (UAA, UAG, and UGA), also called stop codons or nonsense codons.

TLS Online TPP Program

#Id: 3615

#Unit 3. Fundamental Processes

The degeneracy of the code is not uniform. Whereas methionine and tryptophan have single codons, for example, three amino acids (Arg, Leu, Ser) have six codons, five amino acids have four, isoleucine has three, and nine amino acids have two.

TLS Online TPP Program

#Id: 3616

#Unit 3. Fundamental Processes

A reading frame without a termination codon among 50 or more codons is referred to as an open reading frame (ORF).

TLS Online TPP Program

#Id: 3618

#Unit 3. Fundamental Processes

Minimum degenerated probes can be derived from the minimum degenerating area of any protein.

TLS Online TPP Program

#Id: 3619

#Unit 3. Fundamental Processes

Peptide bond formation takes place through Proton Shuttle reaction.