Phase-contrast microscopy is suitable for observing single cells or thin cell layers.

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#Unit 7. System Physiology – Animal

The synapse between a motoneuron and a muscle fiber is called the neuromuscular junction

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#Unit 7. System Physiology – Animal

Action potentials are propagated down the motoneuron, depolarize each adjacent region to threshold. Finally, the presynaptic terminal is depolarized, and this depolarization causes voltage-gated Ca2+ channels in the presynaptic membrane to open.

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#Id: 5478

#Unit 7. System Physiology – Animal

TLS Online TPP Program

#Id: 5479

#Unit 7. System Physiology – Animal

Ca2+ uptake into the terminal causes release of the neurotransmitter acetylcholine (ACh), which has been previously synthesized and stored in synaptic vesicles.

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#Id: 5480

#Unit 7. System Physiology – Animal

ACh is formed from acetyl coenzyme A (acetyl CoA) and choline by the action of the enzyme choline acetyltransferase

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#Id: 5481

#Unit 7. System Physiology – Animal

ACh diffuses across the synaptic cleft to the postsynaptic Membrane of motor end plate, which contains nicotinic receptors