A modification of the agglutination reaction, called agglutination inhibition, provides a highly sensitive assay for small quantities of an antigen. For example, one of the early types of home pregnancy test kits included latex particles coated with human chorionic gonadotropin (HCG) and antibody to HCG.

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#Unit 5. Developmental Biology

T-independent response

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#Unit 5. Developmental Biology

B-Cell Activation

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#Unit 5. Developmental Biology

Generation of antibodies to T-dependent antigens

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#Unit 5. Developmental Biology

Properties of thymus-dependent and thymus-independent antigens

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#Unit 5. Developmental Biology

B cells can be negatively signaled through CD22 and FcγRIIb a receptor that recognizes the presence of IgG containing immune complexes in the blood.

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#Unit 5. Developmental Biology

B-10 B cells release the interleukin IL-10 upon antigenic stimulation, and may serve to reduce inflammation during an ongoing immune response.