TLS Online TPP Program

#Id: 7255


B cells can be negatively signaled through CD22 and FcγRIIb a receptor that recognizes the presence of IgG containing immune complexes in the blood.

#Unit 5. Developmental Biology #Major histocompatibility complex #Part B Pointers
More Pointers
TLS Online TPP Program

#Id: 9632

#Unit 4. Cell Communication and Cell Signaling

Ras has an intrinsically slower rate of GTP hydrolysis, so Ras∙GTP requires the assistance of another protein, GAP.

TLS Online TPP Program

#Id: 10535

#Unit 4. Cell Communication and Cell Signaling

Neurotrophins:
NGF 
Brain derived neurotrophic factor 
Neurotrophin-3 (NT-3)

TLS Online TPP Program

#Id: 6136

#Unit 3. Fundamental Processes

XPC detect distortions = UvrA in E. coli
Formation of the bubble involves the helicase activities of the proteins XPA and XPD (the equivalent to UvrB in E. coli) and the single-strand-binding protein RPA. The bubble creates cleavage sites 5’ to the lesion for a nuclease known as ERCC1-XPF and 3’ to the lesion for nuclease XPG (representing the function of UvrC). In higher cells, the resulting DNA strand is 24–32 nucleotides long. As in bacteria, the DNA strand is released to create a gap that is filled in by the action of DNA polymerase and ligase.
XPB and XPD are both helicases; the XPB helicase is required for promoter melting during transcription, while the XPD helicase performs the unwinding function in NER

TLS Online TPP Program

#Id: 1549

#Unit 2. Cellular Organization

Two main families of motor proteins mediate transport along microtubules:

Kinesins 

Dyneins

TLS Online TPP Program

#Id: 8205

#Unit 2. Cellular Organization

Membranes of late endosomes and lysosomes contain V-class proton pumps that act in concert with Cl- channels to acidify the vesicle lumen.