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TLS Online TPP Program

#Id: 5070

DnaA mutants make replication asynchronous
SeqA mutant cells don’t delay rereplication for 13 minutes
Dam methylase mutants stops rereplication
SeqA-/dam+ accumulation of methylated products
SeqA+/dam- accumulation of hemimethylated products
SeqA-/dam- accumulation of hemimethylated products

#Unit 3. Fundamental Processes #Cell Cycle & Replication #Part B Pointers
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TLS Online TPP Program

#Id: 3847

#Unit 5. Developmental Biology

Adenylate cyclase A (ACA), is responsible for the synthesis of cAMP.
TLS Online TPP Program

#Id: 3848

#Unit 5. Developmental Biology

For stalk and spore maturation, cAMP is produced by adenylate cyclase R (ACR)
TLS Online TPP Program

#Id: 3849

#Unit 5. Developmental Biology

ACR harbours seven transmembrane domains and is embedded in the nuclear membrane of prestalk cells.
TLS Online TPP Program

#Id: 3850

#Unit 5. Developmental Biology

ACG harbours two transmembrane domains & localizes to the membrane of the prespore vesicles.
TLS Online TPP Program

#Id: 3851

#Unit 5. Developmental Biology

ACG act as an osmosensor, so spores formed from the acg- cells will germinate irrespective of the osmotic conditions.
TLS Online TPP Program

#Id: 3852

#Unit 5. Developmental Biology

Adenylate cyclase B (ACB) is normally expressed in prestalk cells, but is upregulated in the prespore region of acg null structures.