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TLS Online TPP Program

#Id: 5383

Age-specific fertility rate - Any given age, Proportion of female offspring that are born to females of reproductive age.

#Unit 10. Ecological Principles #Life Table #Part B Pointers
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TLS Online TPP Program

#Id: 8197

#Unit 2. Cellular Organization

Zellweger syndrome
Autosomal recessive Mutations in any of a dozen different peroxins, the most common being Pex1, cause an impairment in peroxisomal protein import.
TLS Online TPP Program

#Id: 8198

#Unit 2. Cellular Organization

Lysosomes are membrane-enclosed organelles filled with soluble hydrolytic enzymes that digest macromolecules.
TLS Online TPP Program

#Id: 8199

#Unit 2. Cellular Organization

Lysosomes contain about 40 types of hydrolytic enzymes, All are acid hydrolases, work best at acidic pH including: proteases, nucleases, glycosidases, lipases, phospholipases, phosphatases, and sulfatases.
TLS Online TPP Program

#Id: 8200

#Unit 2. Cellular Organization

For optimal activity, of acid hydrolases they need to be: Activated by proteolytic cleavage Requires an acid environment.
TLS Online TPP Program

#Id: 8201

#Unit 2. Cellular Organization

Lysosome an interior pH of about 4.5–5.0
TLS Online TPP Program

#Id: 8202

#Unit 2. Cellular Organization

Most of the lysosome membrane proteins, are highly glycosylated, which helps to protect them from the lysosome proteases