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TLS Online TPP Program

#Id: 5445

Sodium channels can be blocked by a toxin called tetrodotoxin when it is applied to the outside of the cell membrane (activation gates)



#Unit 7. System Physiology – Animal #Nervous system, Neurons, action potential #Part B Pointers
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TLS Online TPP Program

#Id: 8318

#Unit 2. Cellular Organization

Nucleation phase 
Two G-actin molecules bind relatively weakly to each other, but addition of a third actin monomer to form a trimer makes the entire group more stable, acts as a nucleus for polymerization.
TLS Online TPP Program

#Id: 8319

#Unit 2. Cellular Organization

Nucleation phase 
Lag period (Time taken for nucleation) Rate-limiting Step.
TLS Online TPP Program

#Id: 8320

#Unit 2. Cellular Organization

The lag phase can be reduced or abolished entirely by adding premade nuclei.
TLS Online TPP Program

#Id: 8321

#Unit 2. Cellular Organization

Elongation phase

short oligomer rapidly increases in length by the addition of actin monomers to both of its ends, causing filament elongation
TLS Online TPP Program

#Id: 8322

#Unit 2. Cellular Organization

Steady-state phase
G-actin monomers exchange with subunits at the filament ends, but there is no net change in the total length of filaments.
TLS Online TPP Program

#Id: 8323

#Unit 2. Cellular Organization