Nurturing Life Sciences
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#Unit 2. Cellular Organization
The rate of reassociation/renaturation is inversely proportional to sequence complexity.
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Is expression for a second-order rate process of renaturation
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Complexity (denoted by N) is the number of base pairs of unique or nonrepeating DNA in a given segment of DNA
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Consider 5000 bp with 1000 bp (1 Copy), 700 bp (5 Copies) and 100 bp (5 Copies) calculate complexity of genome?
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Viral and bacteriophage genomes have almost no repeated DNA, and L is approximately equal to N.
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Repetitive DNA sequences renature faster than non repetitive DNA due to uniformity of sequence.