Constitutive mutations occur at 8 positions in the operator between +5 and +17 called OC

TLS Online TPP Program

#Id: 8145

#Unit 2. Cellular Organization

Vesicle Type- Clathrin

Transport - trans-Golgi to endosome

Coat Proteins – Clathrin + AP1 complexes

                            Clathrin + GGA

Associated GTPase- ARF

TLS Online TPP Program

#Id: 8146

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 8147

#Unit 2. Cellular Organization

A clathrin molecule,

called a triskelion, is composed of : 

Three heavy chains

Three light chains

TLS Online TPP Program

#Id: 8148

#Unit 2. Cellular Organization

Depolymerization of the clathrin coat into triskelions  by Cytosolic Hsp70

TLS Online TPP Program

#Id: 8149

#Unit 2. Cellular Organization

ARF and Sar1 similar to Ras

TLS Online TPP Program

#Id: 8150

#Unit 2. Cellular Organization

Sar1 is the only GTPase switch protein activated at the ER membrane