Pol a/primase enzyme binds to the initiation complex at the origin and synthesizes a short strand consisting of 10 bases of RNA followed by 20 to 30 bases of DNA called as iDNA.
It is then replaced by an enzyme that will extend the chain. On the leading strand, this is DNA polymerase E; on the lagging strand this is DNA polymerase d. This event is called the polymerase switch.
#Unit 3. Fundamental Processes#Eukaryotic DNA Replication#Part B Pointers
