Terminal transferase (TdT) Adds homopolymer tails to the 3’end of DNA.

TLS Online TPP Program

#Id: 7847

#Unit 1. Molecules and their Interaction Relevant to Biology

The two diastereomers of glucose in its "pyranose" form are called the alpha (a) and beta (B) isomers, which differ in the orientation of the OH at C-1

TLS Online TPP Program

#Id: 7849

#Unit 1. Molecules and their Interaction Relevant to Biology

The pyranose form of glucose dominates (>99%) at equilibrium in aqueous solution

TLS Online TPP Program

#Id: 7850

#Unit 1. Molecules and their Interaction Relevant to Biology

The 6-membered cyclic form of sugars is usually called the “pyranose” form in reference to the cyclic ether pyran.

TLS Online TPP Program

#Id: 7852

#Unit 1. Molecules and their Interaction Relevant to Biology

The pyranose forms of the sugars are more stable than the furanose forms in solution.

TLS Online TPP Program

#Id: 7853

#Unit 1. Molecules and their Interaction Relevant to Biology

Thus, D glucose in aqueous solution exists as an equilibrium mixture of 5 compounds. The pyranose form predominates in solution.

aD glucofuranose (0.5%)

aD-glucopyranose (37%)

aldehydo- -glucose (0.003%)

bD-glucofuranose (0.5%)

bD-glucopyranose (62%)

TLS Online TPP Program

#Id: 7854

#Unit 1. Molecules and their Interaction Relevant to Biology

The optical activity of a stereoisomer is expressed quantitatively by its optical rotation.

The number of degrees by which plane-polarized light is rotated on passage through a given path length of a solution of the compound at a given concentration.