Humans have the enzyme hSMUG1, which removes any U residues that occur in single-stranded DNA during replication or transcription.  Two other human DNA glycosylases, TDG and MBD4, remove either U or T residues paired with G, generated by deamination of cytosine or 5-methylcytosine, respectively.

TLS Online TPP Program

#Id: 9060

#Unit 4. Cell Communication and Cell Signaling

Increased cAMP; PKA active, increased glycogen breakdown, and decreased glycogen synthesis

TLS Online TPP Program

#Id: 3684

#Unit 2. Cellular Organization

The “introns early” hypothesis is the proposal that introns have always been an integral part of the gene.  Genes originated as interrupted structures, and those now without introns have lost them in the course of evolution.

TLS Online TPP Program

#Id: 3207

#Unit 3. Fundamental Processes

Deamination of cytosine creates a U-G base pair. Uracil is preferentially removed from the mismatched pair

TLS Online TPP Program

#Id: 4829

#Unit 13. Methods in Biology

In case of type I or type-1 error, the null hypothesis is rejected though it is true whereas type II or type-2 error, the null hypothesis is not rejected even when the alternative hypothesis is true.

TLS Online TPP Program

#Id: 6392

#Unit 2. Cellular Organization

Stimulation of b-galactosidase synthesis by cAMP with wild-type and mutant CAP.