Nurturing Life Sciences
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#Unit 3. Fundamental Processes
Guanine is deaminated to xanthine.
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Nitrous acid induces transitions in both directions, A:T ↔ G:C.
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The +vely charged acridine dyes or acridine orange are potent mutagens that induce frameshift mutations by Intercalation.
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The +vely charged acridine dyes also causes Slippage and Slippage causes COPY NUMBER MUTATION.
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COPY NUMBER MUTATION are analyzed by simple PCR technique.
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Alkylating agents are chemicals that donate alkyl groups to other molecules as nitrogen mustard, and methyl and ethyl methane sulfonate (MMS and EMS).