Deamination of the human apolipoprotein B mRNA takes place by an enzyme called APOBEC1

TLS Online TPP Program

#Id: 6325

#Unit 3. Fundamental Processes

The b-subunit is obviously the determinant of rifampicin sensitivity or resistance.

TLS Online TPP Program

#Id: 758

#Unit 3. Fundamental Processes

The overall reaction rate for the bacterial RNA polymerase can be as fast as 40–50 nucleotides/second at 37°C for most transcripts; this is about the same as the rate of translation (15 amino acids/sec), but much slower than the rate of DNA replication (800 bp/sec).

TLS Online TPP Program

#Id: 759

#Unit 3. Fundamental Processes

Four Steps for bacterial transcription

1. Promoter search->closed promoter complex -> open promoter complex

2. Abortive transcription->Promoter Escape->Initiation from +1 TSS 

3. Elongation

4. Termination

TLS Online TPP Program

#Id: 760

#Unit 3. Fundamental Processes

Promoter search->closed promoter complex -> open promoter complex

TLS Online TPP Program

#Id: 761

#Unit 3. Fundamental Processes

Sigma factor ensures that bacterial RNA polymerase initiates transcription from specific sites, also reduces binding to nonspecific sequences.

TLS Online TPP Program

#Id: 762

#Unit 3. Fundamental Processes