In nonsense mediated decay  in the addition of multiple lysines to the end of the protein (AAA is the codon for lysine) and stalling of the ribosome at the end of the mRNA. 

TLS Online TPP Program

#Id: 10491

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 6765

#Unit 3. Fundamental Processes

P bodies are dense cytoplasmic domains many times the size of a ribosome. They are sites of translational repression that contain no ribosomes or translation factors. They are also major sites of mRNA degradation in the cytoplasm. Exon-junction complexes upf complex functions in nonsense-mediated decay and induces degradation of the mRNA by P body–associated 5′→3′ exoribonuclease XRN1 

TLS Online TPP Program

#Id: 6293

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 10280

#Unit 6. System Physiology – Plant

TLS Online TPP Program

#Id: 3533

#Unit 2. Cellular Organization

A functional gene can be located through the use of an expressed sequence tag (EST)