The metaphase scaffold consists of a dense network of fibers. Threads of DNA emanate from the scaffold, apparently as loops of average length 30 to 90 kb.

TLS Online TPP Program

#Id: 657

#Unit 3. Fundamental Processes

 Telomeric sequences can be written in the general form Cn(A/T)m, where n >1 and m is 1 to 4.

TLS Online TPP Program

#Id: 658

#Unit 3. Fundamental Processes

TTAGGG repeats with size of 3–20-kb are telomeres of human chromosomes.

TLS Online TPP Program

#Id: 659

#Unit 3. Fundamental Processes

Telomeric sequence is the extension of the G-T–rich strand, which for 14 to 16 bases is usually a single strand.

TLS Online TPP Program

#Id: 660

#Unit 3. Fundamental Processes

G-tail is probably generated because there is a specific limited degradation of the C-A–rich strand.

TLS Online TPP Program

#Id: 661

#Unit 3. Fundamental Processes

Drosophila telomeres are an exception, consisting of terminal arrays of retrotransposons.

TLS Online TPP Program

#Id: 662

#Unit 3. Fundamental Processes

Telomeres cluster on the nuclear envelope just prior to homologous chromosome synapsis during meiosis.