cas1, cas2, and cas4 required to create protospacer sequences Cas1 is  integrase, whereas Cas2 is a ribonuclease. In contrast, of other Cas proteins, Cas6 is involved in expression and processing of the CRISPR cluster and Cas3 in the interference of viral infection.

TLS Online TPP Program

#Id: 2762

#Unit 13. Methods in Biology

Lane 3 depicts the behavior of the same DNA bound to two proteins. The mobility is reduced still further because of the greater mass of protein clinging to the DNA. This is 

called a supershift. 

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#Id: 1342

#Unit 4. Cell Communication and Cell Signaling

HER3 lacks a functional kinase domain

TLS Online TPP Program

#Id: 913

#Unit 13. Methods in Biology

bromodeoxyuridine (BrdU) is rapidly phosphorylated and incorporated in its place into newly synthesized DNA hence BrdU is used to detect replicating cells.

TLS Online TPP Program

#Id: 9459

#Unit 4. Cell Communication and Cell Signaling

Ligand binding triggers a conformational change in the JAKs & they phosphorylate each other on a critical tyrosine in the activation loop which greatly enhances kinase activity

TLS Online TPP Program

#Id: 3509

#Unit 2. Cellular Organization

The homology between two genes can be plotted in the form of a dot matrix