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TLS Online TPP Program

#Id: 6892

To modify DNA at a new position requires the action of a de novo methyltransferase, which recognizes DNA by virtue of a specific sequence. It acts only on unmethylated DNA to add a methyl group to one strand.


#Unit 3. Fundamental Processes #Chromatin Remodelling & Epigenetics #Part B Pointers
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TLS Online TPP Program

#Id: 8932

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 8933

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 8934

#Unit 2. Cellular Organization

Spindle assembly checkpoint pathway is active until every single kinetochore has attached properly to spindle microtubules
TLS Online TPP Program

#Id: 8935

#Unit 2. Cellular Organization


TLS Online TPP Program

#Id: 8936

#Unit 2. Cellular Organization

When a kinetochore is unattached, the outer kinetochore component Knl1 is phosphorylated by the checkpoint kinase Mps1.
TLS Online TPP Program

#Id: 8937

#Unit 2. Cellular Organization

Phosphorylated Knl1 binds the checkpoint protein kinase Bub1-Bub3 and checkpoint protein BubR1. These three proteins, recruit the Mad1-Mad2 complex to the kinetochore.