Phosphorylated Knl1 binds the checkpoint protein kinase Bub1-Bub3 and checkpoint protein BubR1. These three proteins, recruit the Mad1-Mad2 complex to the kinetochore.

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#Id: 6091

#Unit 10. Ecological Principles

Biosphere Reserves The concept of Biosphere Reserves (BR) was launched in 1975 as a part of UNESCO’s

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#Id: 605

#Unit 2. Cellular Organization

N protein prevents termination in the early operons of lambda and it works together with the products of the bacterial genes nusA, nusB, nusE, and nusG.

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#Id: 7157

#Unit 5. Developmental Biology

Gray Crescent 

The region opposite the point of sperm entry, where the greatest displacement of cytoplasm occurs (Gastrulation will begin)

Vegetal rotation: Vegetal cells asymmetrically press up against the inner blastocoel roof on the dorsal side.

Bottle cell formation and invagination: Localized apical constriction at the dorsal blastopore lip creates anisotropic forces that foster invagination.

Involution and cell migration: The leading edge of invaginating cells crawls up onto the blastocoel roof.

Convergence and extension: The targeted medial-to-lateral intercalation of cells on the midline (convergence) drives anterior-posterior axis elongation (extension).

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#Id: 192

#Unit 5. Developmental Biology

At lower concentrations of activin, genes were not activated, and the “default” gene expression instructed the cells to become blood vessels and heart.

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#Id: 6363

#Unit 2. Cellular Organization

There are 4 genes (I, Z, Y, A), 2 Promoters and 3 lac operators in Lac operon

The major O1 lac operator lies adjacent to promoter

The O1 operator extends from position -5 just upstream of the mRNA start point to position +21 within the transcription unit.