At the end of a normal chromosome 9 is a potential cancer-causing gene called c- ABL.   As a result of the translocation, part of the cABL gene is fused with the BCR gene from chromosome 22. The protein produced by this BCR–c-ABL fusion gene is much more active than the protein produced by the normal c- ABL gene.

TLS Online TPP Program

#Id: 9314

#Unit 4. Cell Communication and Cell Signaling

3 or 4 cGMP molecules must bind to each channel in order to open it; because of this cooperative allosteric interaction, channel opening is very sensitive to small changes in cGMP levels.

TLS Online TPP Program

#Id: 2432

#Unit 3. Fundamental Processes

When the RNA polymerase reaches the termination site, rho first freezes the structure of the polymerase and then invades the exit channel to destabilize the enzyme, causing it to release the RNA.

TLS Online TPP Program

#Id: 1256

#Unit 7. System Physiology – Animal

ADH directs the insertion of water channels, AQP2

TLS Online TPP Program

#Id: 10423

#Unit 4. Cell Communication and Cell Signaling

Tumor cells secrete a protein plasminogen activator that converts the serum protein plasminogen to the active protease plasmin.

TLS Online TPP Program

#Id: 10345

#Unit 4. Cell Communication and Cell Signaling

T1 and T2 Transitional B Cells