Multipotent adult stem cells play major roles in organisms with high regenerative capabilities, such as hydra, axolotl, and zebrafish. one cell type.

TLS Online TPP Program

#Id: 10456

#Unit 4. Cell Communication and Cell Signaling

A highly specific inhibitor imatinib (Gleevec), which

binds directly to the active site of the ABL kinase and holds it in an inactive conformation to inhibit its kinase activity, is lethal to CML cells

TLS Online TPP Program

#Id: 10458

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 10459

#Unit 4. Cell Communication and Cell Signaling

Inappropriate production of nuclear transcription factors such as FOS, JUN, and MYC can induce transformation.

TLS Online TPP Program

#Id: 10460

#Unit 4. Cell Communication and Cell Signaling

Burkitt’s lymphoma

translocation between chromosomes 8 and 14

TLS Online TPP Program

#Id: 10461

#Unit 4. Cell Communication and Cell Signaling

In Burkitt’s lymphoma cells, 

MYC is translocated close to an antibody gene, leading to overproduction of MYC

TLS Online TPP Program

#Id: 10462

#Unit 4. Cell Communication and Cell Signaling

MYC gene encodes a basic helix-loop-helix protein

include MAD, MAX, and MNT