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Three protein-coding genes are found in bithorax complex: 
Ultrabithorax (Ubx)
Abdominal A (abdA) 
Abdominal B (AbdB) 


#Unit 5. Developmental Biology #Drosophila Development #Part B Pointers
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#Unit 8. Inheritance Biology

Tandem duplication - Duplicated chromosome segment is adjacent to the original segment.



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#Unit 8. Inheritance Biology

In heterozygotes DUPLICATIONS - The pairing and synapsis of homologous regions require that one or both chromosomes loop and twist. 



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#Unit 8. Inheritance Biology

EFFECTS OF CHROMOSOME DUPLICATIONS - Bar phenotype in Drosophila



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#Unit 8. Inheritance Biology

Duplications and deletions often arise from unequal crossing over.


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#Unit 8. Inheritance Biology

Chromosome duplications are one way in which new genes evolve.


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#Unit 8. Inheritance Biology

Segmental duplications have played an important role in the evolution of human chromosomes; about 4% of the human genome consists of segmental duplications. 


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