Mitochondrial fusion and fission are mediated by a set of GTPase enzymes:

Mitochondrial fusion -MFN1/2 & OPA1

Mitochondrial fission- DRP1

TLS Online TPP Program

#Id: 6896

#Unit 3. Fundamental Processes

UHRF1 also interacts with methylated histone H3, which connects the maintenance of DNA methylation with the stabilization of heterochromatin structure

TLS Online TPP Program

#Id: 7914

#Unit 2. Cellular Organization

Matrix-targeting sequences

Located at the N-terminus

Usually 20–50 amino acids in length

Rich in hydrophobic amino acids, positively charged basic amino acids (arginine & lysine), and hydroxylated ones (serine and threonine)

Amphipathicity of matrix-targeting sequences is critical to their function

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Integrins function as transmembrane linkers (integrators) between the extracellular matrix and the actin cytoskeleton.

TLS Online TPP Program

#Id: 652

#Unit 3. Fundamental Processes

The Ames test uses a strain of S. typhimurium that is mutant for the operon responsible for the biosynthesis of the amino acid histidine.

TLS Online TPP Program

#Id: 9233

#Unit 6. System Physiology – Plant

Photorespiration stimulates nitrate assimilation in C3 plant roots, probably by increasing NADH availability in the cytosol.

Photorespiration is positively correlated with growth under nitrogen limitation