Adaptation to water viscosity

Some small aquatic organisms exploit the high viscosity of water by evolving large appendages

Streamlined shapes that reduce the drag caused by the high viscosity of water

TLS Online TPP Program

#Id: 9084

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 9085

#Unit 4. Cell Communication and Cell Signaling

Subunit B recognizes and binds to specific gangliosides on the surface of intestinal epithelial cells and provides a route for subunit A to enter. 

TLS Online TPP Program

#Id: 9086

#Unit 4. Cell Communication and Cell Signaling

A1 associates with ARF6, a small G protein in host cells which are accessible only when ARF6 is in its active (GTP-bound) form. 

TLS Online TPP Program

#Id: 9087

#Unit 4. Cell Communication and Cell Signaling

Association with ARF6 activates A1, which catalyzes the transfer of ADP-ribose from NAD to the critical Arg residue in the P loop of the  subunit of Gαs. 

TLS Online TPP Program

#Id: 9088

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 9089

#Unit 4. Cell Communication and Cell Signaling

ADP-ribosylation blocks the GTPase activity of Gαs and renders Gαs permanently active.