CD spectra is used to

determine whether proteins are properly folded, 

estimate the fraction of the protein that is folded in either of the common secondary structures, and

monitor transitions between the folded and unfolded states.

TLS Online TPP Program

#Id: 700

#Unit 3. Fundamental Processes

As a general rule, increased processivity reduces the likelihood of slippage at long sequence of dTn:dAn or frameshift mutation 

TLS Online TPP Program

#Id: 701

#Unit 3. Fundamental Processes

Which of the polymerase can recognise A-A complimentary base pairs as normal

1. I 2. II 3. III     4. IV 

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#Id: 702

#Unit 3. Fundamental Processes

The replicase activity of DNA polymerase III was originally discovered by a conditional lethal mutation in the dnaE locus, which codes for the 130 kD, a subunit that possesses the DNA synthetic activity.

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#Id: 703

#Unit 3. Fundamental Processes

The 3’–5’ exonucleolytic proofreading activity is found in E, coded by the dnaQ gene

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#Id: 704

#Unit 3. Fundamental Processes

Mutations in dnaQ showed increased mutation frequency with by103-folds

TLS Online TPP Program

#Id: 705

#Unit 3. Fundamental Processes

Proofreading typically decreases the error rate in replication from10-5 to 10-7 per base pair replicated.