Two major classes of actin-nucleating proteins:

1. Formins nucleate the assembly of unbranched filaments 

2. Arp2/3 complex nucleates the assembly of branched actin networks

TLS Online TPP Program

#Id: 3084

#Unit 3. Fundamental Processes

Anucleate cells of normal size are generated by partition mutants, in which the duplicate chromosomes fail to separate.

TLS Online TPP Program

#Id: 3085

#Unit 3. Fundamental Processes

Long filaments form when septum formation is inhibited, but chromosome replication is unaffected.

TLS Online TPP Program

#Id: 3086

#Unit 3. Fundamental Processes

Minicells form when septum formation occurs too frequently or in the wrong place, with the result that one of the new daughter cells lacks a chromosome. 

TLS Online TPP Program

#Id: 3087

#Unit 3. Fundamental Processes

he gene ftsZ plays a central role in division. Mutations in ftsZ block septum formation and generate filaments.

TLS Online TPP Program

#Id: 3088

#Unit 3. Fundamental Processes

FtsZ functions at an early stage of septum formation. Early in the division cycle, FtsZ is localized throughout the cytoplasm, but prior to cell division.

TLS Online TPP Program

#Id: 3089

#Unit 3. Fundamental Processes

FtsZ is a GTPase that forms a ring on the inside of the bacterial envelope. It is connected to other cytoskeletal components.