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TLS Online TPP Program

#Id: 8445

Right-handed helical conformation has 3.6 residues per turn and 1.5A/aa.

#Unit 1. Molecules and their Interaction Relevant to Biology #Conformation of proteins #Part B Pointers
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TLS Online TPP Program

#Id: 10320

#Unit 4. Cell Communication and Cell Signaling

The tumor cells may acquire additional oncogenic mutations that allow them to escape the immune system.
TLS Online TPP Program

#Id: 10321

#Unit 4. Cell Communication and Cell Signaling

The tumor down regulates the expression of class I MHC proteins
TLS Online TPP Program

#Id: 10322

#Unit 4. Cell Communication and Cell Signaling

Sometimes the tumor cells up-regulate the expression of anti-apoptotic proteins like BCL-2.
TLS Online TPP Program

#Id: 10323

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 10324

#Unit 4. Cell Communication and Cell Signaling

PD-1 has a structure similar to CTLA-4 and when activated negatively regulates T-cell function by inducing apoptosis of activated T cells. 
TLS Online TPP Program

#Id: 10325

#Unit 4. Cell Communication and Cell Signaling

Monoclonal Antibodies Against Immune Checkpoint Molecules to Treat Cancers